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Can Too Much Protein Kick You Out of Ketosis?The answer to the question of whether too much protein bumps you out of ketosis is it depends. Some people
find that higher amounts of protein interfere with their ability to maintain
ketosis, while others can tolerate more protein without problems. You may have heard that gluconeogenesis—in which your body makes glucose from non-carb sources—increases during high protein consumption. This idea makes some keto dieters fearful of protein. Keto-friendly proteinThe reality is that gluconeogenesis happens continuously, regardless of your protein intake, because certain tissues in your body rely exclusively on glucose. These include your red blood cells, renal
medulla (the innermost part of your kidney), and testes. When you are not consuming carbs that are easily converted to glucose, the body uses this
method to produce glucose. In other words, gluconeogenesis makes it possible to maintain a state of ketosis by ensuring that glucose-dependent tissues don’t malfunction. But here’s something you should also know: Too much protein may decrease your ketone levels since protein has a moderate insulin-stimulating effect. (In situations where insulin increases, fatty oxidation decreases, which inhibits ketone production. )  Furthermore, research suggests that the amino acid alanine may be antiketogenic—meaning, it suppresses ketone production.